Thanks Steve, I hadn't noticed that before.

I did more testing and verified Realband 2018_4_0 was being launched each time. Also checked permissions and tried Run as Admin but that didn't change anything.

Turns out if I don't close the Windows Volume Mixer window and reopen Realband, then it shows up like the second picture above. If I close Realband and the Volume Mixer window, then the Realband Icon shows as in the first picture but the volume level still changes to whatever the speakers output level is.

I tried Biab 2018 again and the volume level stays at whatever it was set to last time it was used.