So I'm not sure whether the update is causing this issue, but throwing that information in there anyway.

Note that I checked the "direct input" box when loading the RT, and Guitar Rig is working fine in Reaper when loaded into the FX slot. Also note, that the Guitar Rig interface is loading just fine, it's just the RT is not being affected in any way by the application.

Thanks in advance!

Edit: Just rebooted the program and now it's working...