Deacon, I've had 2018 BIAB and prior versions run in this manner of hard drives. My SSD is the C:\ and the HDD is the D:\ drive. All RTs and drums are located on D:\BB and the program is on C:\BB. No issues at all with latency on the real tracks being on a slower disk.

In general I keep all my Win10 software and other apps on C:\ and all data files on D:\ since it's a much larger disk.




Steve

BIAB/RB 2022, Pro Tools 2020, Korg N5, JBL LSR 4328 Powered Monitors, AKG/Shure Mics.
PC: Win11 PRO, 4 TB M2 SSD, 2 TB HD, 128 GB Memory