Today and with previous files I have found that I am experiencing pops and crackles with my files.
I use BIAB for practise. I take a song form and work it around different keys, sometimes I fiddle a little with the structure.
After working a piece for several days I often find that the song crackles.
After investigation I have found that its not the latency on my Focusrite Liquid 56, My machine is a WIn7 64 Core i7 with 12 gig - so its not the CPU.

I do find that for BIAB I have to increase latency to 512 whereas Cubase 8 runs at 64.

I think after tweaking the file several times it gets corrupted and has to be abandoned. If I change the song I discovered the crackles go away - providing the sound device is set to 512.

Z

Win 11 64, Asus Rog Strix z390 mobo, 64 gig RAM, 8700k