OK - Here's a lineup of my favorite youngsters playing great music with guitar-centric (or in the case of Vulfpeck, bass-centric) orchestration.

Vulfpeck (eddie, you might want to look away, these kids are from Ann Arbor as far as I can tell). Really tight funk. Everyone plays everything except for Joe Dart the bass player - he just kills it on funky bass and I don't mean slapping.

Some of my faves from them:
https://youtu.be/w9COHCrwNQs (nice strat solo about 2:30-2:50)
https://youtu.be/4dpvyZBKg6Q (insane strat playing on this one, with slide thrown in here and there)
https://youtu.be/jRHQPG1xd9o (guest vocalist has some Al Green going, for sure - the guy playing the strat in this one also is a mean keyboard player, and drummer)

If you enjoy this straight up excellent soul and funk, subscribe to their YouTube channel - they'll get paid through the advertisement revenue they are now getting by having so many views on YouTube.

Colony House
Just great pop-rock. No guitar pyrotechnics, but slick riffs and a great overall sound. These guys are getting huge press. Radio play, who knows - but they've been on the Today show. The riff they do on the back end of the chorus sections is great in this one.
https://youtu.be/IBTB54ty-tc
https://youtu.be/DkfBxIH0g0k (throwback sound on this one to many different eras inside of one song)
https://youtu.be/Y4WkY30Sxd0 (same song, played live on Conan - lead singer busted a string on this one)

Silversun Pickups (these guys are more label supported and have been around for 15 years or so - lead singer's voice is a love or hate sound - everytime I hear it, it intrigues me and I listen more)
https://youtu.be/XBdeNVb3SdM (video is a bit disturbing, but it does feature some of their unique modern riffy guitar sound)
https://youtu.be/AG8fugqFn9Q (probably their most popular song - very heavy riff opening repeated at different points in the song)

Death Cab for Cutie (Band just broke up, I came to liking them late - the album Kintsugi is fantastic if you like 80's new wave guitar based sound)
https://youtu.be/srvcc8izHSU
https://youtu.be/io9ivuo4r6Q

Alabama Shakes (one of the biggest bands in the entire industry right now, with GREAT guitar work)
https://youtu.be/x-5OX7CO26c
Same song on SNL live
https://youtu.be/t3Lu1WbImPE

Not necessarily favorites, but just more proof that the guitar is not dying.

Bruno Mars (is there a bigger star right now? - so glad this sound with it's funk guitar and keyboards is being appreciated by the kids of today)
https://youtu.be/_8cK15Iv5qM (Live on SNL)

Kings of Leon
Live on Fallon:
https://youtu.be/SZDmwP1rOfM