Hi,

Band-in-a-Box 2008 itself is compatible with Windows 10 (assuming your installation discs still work), but the Roland Virtual Soundcanvas softsynth that comes with it won't even install, so you'd have to use the Microsoft GS Wavetable Synth for MIDI sounds (which would have a lot of latency, and rendering to WAV won't work.

I'd definitely recommend upgrading, the 2018 version will work much better.

Thanks
Kent
PG Music