You really need to check out that pref button as it resolved my problem. I have my ST on my D drive and BIAB on an external and it works fine now that I have BIAB pointed to the correct place. You have to open BIAB as administrator then midi->midi driver set up then VST/DXI synth settings then see if ST appears as one of your choices.....if it doesn't then BIAB doesn't see it at all on your computer. If it does then if you select SampleTank then you can use the pref button to point BIAB to exactly where your installation of ST resides. Hope this helps.