This is a generic response but....

By and large my eight Mac years after leaving decades of Windows has been hassle free — nearly seamless; however the few issues I’ve had have been nearly all with permissions. I’d check the Izotope folders and insure that your “home name” has read/write for all of them. I have encountered apps that unbeknownst to me altered permissions in folders that did not “belong” to them.

FWIW,

J&B