The real advantage of using Spectral Editing over a de-esser is you can chop out the offending squeak, pop or whatever without affecting other parts of the signal. It is also possible to knock out very low frequencies if that is what is require.

IZotope RX8 will also do this but I’ve found it far easier just to use Reaper’s Spectral Edit as it is just a part of the track editing process. Once you do it a few times it becomes quite simple to go to the Spectral View on a track and actually see the offending noise. From there it is easy to reduce the level of the offending part (or eliminate it). Sometimes a reduction sounds more natural.

Try new stuff it is fun.

Tony

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