Gram,
Most likely the driver that you are using is not compatible with WIndows Vista. What I would recommend doing is going to the website of the manufacturer of the interface, and seeing if they have an updated driver for Vista. Until you clear that exclamation mark in the Device Manager, it is not going to function. If the interface is an older device, and no updated driver is available, you'll need to purchase a new one.

Make sure that you get the right version driver, i.e., are you running Vista 32 bit or Vista 64 bit. The driver has to be the correct one.

Gary

I'm blessed watching God do what He does best. I've had a few rough years, and I'm still not back to where I want to be, but I'm on the way and things are looking far better now than what they were!