Hey thanks for all your replies.

Rharv, that's what I thought: to assign the directory in audio prefs to the drive letter. But, then when I save, do the tracks stream from C:? In other words, are the tracks to E: just temp tracks, or do they stream always from E:?

ROG: I use an SATA 10,000 rpm veloci-raptor for my external drive, and it seems to handle the loads okay so far. We'll see when I get more tracks and plugins involved.