Joe,

Any of the Fender amp simulations, with a fairly clean setting will help. Some compression before the amp can help as well. Spring reverb is nearly a must. I will see if I can pull some settings from old projects where I did some twangy picking using Amplitube 1 LE. The latest version has much more tweakability - but I would just start with Fender amp models without any effects and see what you get. Perhaps you've already been down this road? I can get a good twangy country tone with my Strat through Amplitube. I'll see what I can dial up and perhaps post here for your perusal.