Interesting idea.

You can also do the same thing in BIAB. You could generate an arrangement - freeze all the tracks except one and then change the chords. The changed chords will only affect the unfrozen track which will now follow the new chords... All the other instruments will be frozen and so will be following the original chords.

I'm wondering if this is in fact what Ian was suggesting in the previous post.

I just tried this in BIAB to generate a guitar solo - I used some interesting chord substitutions and it certainly made for a more varied solo! The solo still "worked" over the original arrangement but it was more interesting than a RT solo that just followed the original chords..