Maybe make all you're changes in Biab and then open it in Real Band. Never heard of that problem before. RB always has worked for me after I changed my drivers to MME from Asio. Also in Windows audio properties you might try (do not map this device) for AISO related problems. You don't need Asio unless you are playing a live Midi device using a soft-synth. This might not be any of you're problems as I'm not a PG products genius.