I suggest the first thing to try is increasing the ASIO buffer from 256 to 512. It seems to work better if you access the M-audio panel through Real Band Audio Preferences. From AUDIO PREFERENCES hit the DRIVERS button, then the ASIO DRIVERS CONTROL PANEL button. This should take you to the M-audio settings.

Why it works better by this method is a mystery, but it's worth doing.

Get back to us if it still doesn't work.

ROG.