And, once the MIDI plays an instrument to produce audio, Amplitube can affect that audio.

This is important because if you render the audio within BIAB, Amplitube will affect the final render... but if you export a MIDI file, load that MIDI into another program, and don't have Amplitube in that other program as an effect on that track, you won't hear anything from it.

Best,
Tom Smith
Win10/64 • i7-8700K • 24 GB RAM
BIAB 2025 • Reaper 7 • Izotope MPS
AKG C1000S • IK iRig I/O Pro