I am currently using a Line 6 Toneport UX1 on both Win XP and Win 7 64 bit Professional computers.

It has 1 Mic and 1 Inst input on front and a Headphone Jack.
There are 2 line Inputs and a Monitor Input on the rear along with the USB connection and 2 Analog Outs.

Note that I had to download Pod Farm 2 and a Driver from the Line 6 website before Win 7 would recognize the UX1.
The original Toneport/Gearbox Driver and application installation disk would only work with Win XP

Gearbox and POD farm applications have different interfaces and Tone names which requires some relearning and experimentation.

The UX1 has been discontinued and replaced by the POD Farm units.

So far I have only tried to record one input (Mic or Guitar or Midi Keyboard) at a time.