I Googled your error message and now believe that your registry has become corrupted. The first step would be to scan for and remove any malware or viruses. After doing so, read and apply the tips found here:

http://www.errorsfixer.org/articles/an-unhandled-exception-occurred

It's a trusted site.

Important note: In the future, help us to help you by giving more details about your setup. That's actually quicker in the long run.