I second everyone suggestions as well Herb gets stellar results with Focusrite, and they are hard to beat. I have as some others do the Presonus. Great interfaces, with one exception. I have the 1818 VSL, and it seems a little shakier driver wise than the other smaller units, at least from what i am reading. I hear on the forum Presonus is working on a new driver for the 1818 as wee speak, hopefully real soon it will be out with some cool enhancements. I do not hear this about the 22 VSL or the 44 VSL. They seem fine.

I love the VSL it seems to set Presouns apart a bit, although Focusrite has a effects suite built in as well i thing the VSL is a tad more complete and forward. I do think any of these are great units. What Guitarhacker said about native ASIO is important.

Lastly one of the big advantages i see to Presonus over any others is the free Studio one artist version software. Artist only real limitation is that it does not allow third party Plugins with a few exceptions like Melodyne, kontakt, and a couple more. But other than that it is a real nice DAW that seems to back up BiaB/RB very nicely. maybe not quite as feature rich as Sonar yet, but certainly very powerful. If you have melodyne Studio one was the first to add ARA integration so that audio editing in Melodyne was only a click away and seamless. Also their version of track lanes or comping is so simple and easy. Studio one artist comes with a nice effects suite, and even the really cool fat channel strip, and a basket load of samples and looped content. Oh and fat channel is built into the interface as well.

HP Win 11 12 gig ram, Mac mini Sonoma with 16 gig of ram, BiaB 2025, Realband, Reaper 7, Harrison Mixbus 9 32c , Melodyne 5 editor, Presonus Audiobox 1818VSL, Presonus control app.