Is this something you downloaded from the internet? There's so many ways a downloaded midi file could not be compatible with your setup you don't even want to go there until you have a good understanding of how midi works. You could download 10 files that play fine then suddenly you go to another site and none of those files play properly. Without going into details, those tend to be created on somebody's specific setup and they have a bunch of non standard commands hidden in them that only work on a Korg keyboard or something. This is guaranteed to drive you crazy until you realize that not all midi files are created equal. I've downloaded hundreds of files and I still have a few that I have no clue why they don't work. Usually, there's program change or other commands in the event list. The big clue from you is you say the problem happens when you start the file from the beginning. That certainly sounds like a program change or a sysex string in the beginning of the file. If you don't see it in the instrument track itself, it may be in a separate track that is just used for data. At first glance all the other tracks look empty but when you open the event list for each "empty" track, there's all this stuff in one of them. It can get very tricky. With a file like that, I find it easier to just search the internet for another version of the song.

Bob

Biab/RB latest build, Win 11 Pro, Ryzen 5 5600 G, 512 Gig SSD, 16 Gigs Ram, Steinberg UR22 MkII, Roland Sonic Cell, Kurzweil PC3, Hammond SK1, Korg PA3XPro, Garritan JABB, Hypercanvas, Sampletank 3, more.