bob,
Most of the time I only use RB, nothing else. Booting up from scratch I still get problems.
If the oxygen was set to 24, then it would have NEVER worked.. but it does work sometimes. I think the OXYgen had some problems though, and I'm not sure what all it might be affecting. So I took it out of the equations and started using a Focusrite 2i4. It also has problems with ASIO, but not the same ones as the oxygen.