I'd try changing the chords up a third or a fifth as my first two guesses so the scales stay related.

B chord up a fifth yields an F# blues scale in the long run, which may get some usable licks.
Up a third makes it a D# blues scale which may also yield some interesting licks...
Yet another trick is to tune the solo to the scale using OBTune or such, forcing any D natural to D sharp.
Lots of creative ways these days.Just a couple ideas to experiment with.

Most important part is to have fun playing with it.


I do not work here, but the benefits are still awesome
Make your sound your own!