Sounds like it should be an interface problem, like bit depth and sample rate not the same in the software as on the hardware. Like I use 24 bit, 48000 sample rate, only because that is what I use in Pro Tools and I got tired of having to remember to change my interface depending on which program I want to use. And when I go back and forth from one to the other, it REALLY gets tedious.

That's all I got though....