I'm running W10, the latest BIAB and a 2nd Gen Scarlet 2i2 with latest ASIO drivers. BIAB reports 6ms latency and the ASIO driver reports 44.1KHz sample rate and buffer size 128. Only small issue I seem to be having is if I let the computer go into sleep mode BIAB seems to somehow get out of sync with the 2i2. Only way to clear the issues is to re-start BIAB.

Had troubles a few months ago using this 2i2 with an older (Samsung) laptop which I'd upgraded from W8 to W10. That laptop never seemed trustworthy for live use after the "upgrade". Extreme long boot time, etc., and the Scarlet never worked reliably with BIAB if I also had some other audio app open, such as Transcribe. The new Lenovo seems much more sympatico with the 2i2.