I started digital recording with PowerTracks ProAudio. It is a great sequencer, pretty powerfull and nicely equiped with a set of fine VST's you can use to improve your production. Don't let the (sorry to say this) poor GUI fool you: this is a good recording software.

I currently use Cubase 5. It works great with my digital mixer/DAW controller. The VST's that come with it are fantastic. Cubase works intuitive to me, more than PTPA. But that ofcourse is just personal.