Which USB port you have should not matter in the grand scheme of things.

I can unplug my Mouse, which has independent drivers built in, and place it into another port, it will use the same drivers. It won't create a new driver for each Serial Bus it accesses.

If you plug in a new device, windows will automatically try to find the best drivers.

Theoretically, if you plugged in sixteen different Audio interfaces, you might get some issues with redundant drivers. This is outside any practical setup.

Ideally, if you are using that many devices and you are no longer going to use them, just wipe your computer.

As someone who was a peripheral junky, and went through about six different keyboards and mice a year, I can assure you that on a properly maintained computer, you should not run into any issues.

Now, we are also talking about computers, there will always be exceptions and random oddities. Either way, if you find yourself three hours into a command prompt, maybe just cut your losses, backup, and reinstall Windows. It will take way less time and effort.

C-sharp when you cross the street… or you’re going to B-flat.

Mikke - PG Music