I wouldn't use a sequencing program to play live BECAUSE of the tracks that offer variables, where a prerecorded WAV never changes, notes never hang, etc. Plus I am lazy and if I can walk in with a mixer, 2 powered speakers and an iPad, I am happy. A guitar, a keyboard, a mic, a stand, and a bag of cables. One trip on a dolly. Boom.

All moot though since my plans are that I will never play live again. I just want to write songs.