Well, i worked with 2018 until 607 came out, mainly for audio issues like vague distortion on transpose and inability to import a second chunk of pure natural 44.1 16kHz cheese .... Voicemeeter banana i tried once, worked ok but too much latency.

As i guess you need the Yamaha USB driver then, latest: Yamaha Steinberg USB Driver 1.10.3
Old UR22 driver: V1.7.1, UR22 Mk2: V1.9.4: older UR22 drivers

There were 2 versions of 1.9.4, 32bit and 64 bit: 1.9.4 PDF

Any chances of trying older versions or even another USB brand interface for a while? Are there any UR22 users on this forum?
Also check this out, as there seem to be a few UR22 versions: UR series forum

PM Ed Doll, helpful guy with some issues with Steinberg's older software licensing and a hardware problem regarding an old Nuendo (RMR) TDIF interface. F