An often made 'mistake': Sometimes higher audio levels seem to sound better ....
.. the only other thing is having to have a separate power supply for the UMC404HD. It's inconvenient, but I also think it's a good idea ..... Jim
That's usually the way with 'cheaply' constructed audio hardware lowering noise levels.
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Now i wonder if these UR22 problems persist if you UNINSTALL all audio drivers completely, especially eventual old Yamaha Steinberg ones, and also remove all entries regarding those in the registry, then properly reboot ... i guess ASIO4all does not help out? F