Hi Noel, thanks for your reply.
I have gone to options and selected Return TO Factory Settings ...

Before returning to factory settings I made some initial changes in the first few measures in teh chart, I then saved the file - closed and re-opened BIAB. It appears to have "held" the changes. THANK YOU!

I have no idea what caused this.., the other thing I just noticed was (prior to returning to factory settings) it also wasn't loading a loop file in the mixer which had previously been saved with the song file several times. WHen opening teh song file the loop file was no there.

I'll keep trying now and hopefully (thanks to your suggestion) I can complete all required changes again and this time hopefully keep them, I'll let you know how I go asap.

Thanks again! so much,
Cheers!