Are you running RB as an administrator?...............YES but shouldn't have too....

I assume you used the Temp Audio Directory setting in Preferences to set the folder, right?.......YES
Does the folder exist?......YES

Does your user have the necessary rights (permissions) to that folder?.....YES.....I am the user

Have your tried a different folder name, or using a path that does not contain spaces just to rule out some weird path issue?.....Like I said I created my own folder called F:\Seq Files Horst\Temp

Like Maybe create an F:\TempAudio folder and point it to there, see if anything changes.....See above...already tried that....

Lastly, is this F: drive an internal hard drive?....No...the F Drive is the USB Hard Drive BIAB\RealBand 2020

What else you got?

Horst Hartung

Windows 10 - RealBand 2020:Build(3); Xtra Styles PAKs 1,2,3,4,5,6,7,8; 64 bit Intel Xeon CPU E5-1620 v3 @ 3.50GHz; 4 TB HD; 550 GB SSD PCIe Drive, 16GB Memory. Behringer UFX1604 Digital Mixer.

Music: https://soundcloud.com/horst_hartung