Yep, in whichever DAW you decide to work in (Reaper, RB, Sonar) find out how to select the mixer as your recordimg input .. and then tinker with the mixer options themselves.
The linked page seemed to mention some convoluted (but cool) options .. like inputs 3/4 on the mixer seem to have magical guitar input options that 1/2 may not for a guitar input.

You'll likely spend a bit of time exploring this, but the manufacturer touts some pretty cool features on that mixer, once learned.

"ZED-10FX’s pre-amps are similar in design to our MixWizard range of mixers, but with a twist! Inputs 3 & 4 have a high impedance jack input capable of taking either a normal line level or a low level input from a guitar pickup. These newly designed inputs have been crafted with the aim of replicating the sound of a classic guitar or instrument tube pre-amp in a combo or head amp."

Have fun experimenting.

"No longer do you need to fiddle around the back of your PC to get to the soundcard inputs, only to find that the levels are all wrong and noisy. Just plug in a USB lead to your ZED, select the USB routing on the mixer and the device on your computer and that’s it! CD quality audio to and from your PC or Mac. Switches and connection through jack socket terminals provide different send/return configurations ... "

I do not work here, but the benefits are still awesome
Make your sound your own!