Which synth?
For many GM synths this happens automatically.
For some synths, inserting a patch change at the beginning of the file and saving it once works better, and yet others (for some reason) Save Group seems to work better.

But there are some that simply have to be reset due to how the synth interacts with RB.
Explain your MIDI set up and we can offer more concrete suggestions.

Heck, the Track Category feature mentioned in a post a few below this one may even help, since it does allow setting up a virtual Save Group scenario that loads when the song loads.


I do not work here, but the benefits are still awesome
Make your sound your own!