It should definitely be possible,
and listening to audio via the 18i8 ASIO should NOT be muddy unless something is set up wrong.
Post screen shots please.
May need to include how the Focusrite Mixer is set up too (separate app).

Also make sure the Focusrite settings match the bitrate you are using in RB.
And you could also try enabling ASIO always on (image below).

Like I said, if you could post screen shots of the settings it would probably help a lot.
Calling the Focusrite 18i8 'the Focusrite box' is ambiguous; try to be clear and concise so we can help better.

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Last edited by rharv; 08/13/20 12:22 PM.
I do not work here, but the benefits are still awesome
Make your sound your own!