I don;t have arthritis but my hands get very sore well the left, I'm a lefty but play right.
I'm a fencer by trade and can spend all day cutting wire with pliers so very jarring.
Over the years I have found a few things to ease the pain in my hands.
I stopped playing steel string and just played nylon which sucked. I found out about "Thomastik Classic S " guitar strings they have a wire core with nylon covering and flat wound bottoms, also very low tension.
There are 2 sizes , the smaller are just wire on the top strings but very low tension.
I used these string on my neglected steel string acoustic and electric and never have looked back...
They are fairly expensive though but worth a try.
The other thing I use when my hand gets really sore is a "You Rock Guitar" It's a midi guitar with touch sensors instead of strings on the fret board and strings to strum if you want..
Unfortunately they went broke but you can still buy them on EBay from china.. Not only do they have the worse name for a guitar they look like a toy... Don't let that fool you they are a amazing bit of engineering..

It's great fun to plug into BIAB and jam along with any instrument sound you like... I keep going to Rhodes piano's..
I also started using my right hand on the MIDI guitar to do lead and unsuccessfully using my left at the same time to do base...