Hello everyone, thanks for all your help. Strangest thing happened, I came back to it the next day and it worked, with MME as the default, so I left it at that, didn't change anything. I'll try ASIO another time, but I am asked if I want to chooses it, but then get a load of other questions.
The only thing that was different, is that from my BIAB (external) drive, the connecting lead is doubled, so I can plug it into 2 usb sockets on my PC. I had been using only one, so maybe that wasn't sufficient.
Simon, I'm just using the internal sound card.
So thanks again everyone, all good at the moment.