Originally Posted By: MarioD
Actually the second dose potentially has more side effects.


To clarify what I was saying: If you have side effects with the first dose, you are more likely to have a slightly more intense response on the second dose since your immune response has been tweaked to mobilize against the antigen that caused the first response. And, if you had no side effects at all on the initial dose, you are still more likely to be have side effects on subsequent vaccinations due to your body mounting an attack on an antigen that it has seen before. The likelihood of side effects always goes up with the boosters in a multi dose series.


Keith
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