Simple answer is No. The standard ASIO can only be used by one program at a time. I set BIAB to MME and Reapear to Asio and can open and run both at the same time. Otherwise, there is rumors of certain ASIO permitting multiple access, but this is a function of the individual driver for specific hardware.


BIAB – 2025, Reaper (current), i7-12700F Processor, 32GB DDR4-3200MHz RAM, 1TB WD Black NVMe SSD, 2TB WDC Blue SSD, 1TB WD Blue, 2 TB SK NVMe, 6 TB External, Motu Audio Express 6x6