The topic of Spleeter has come up in another thread with a link back to this thread.
Some points:

. Someone has created a Spleeter GUI for Windows that removes the complexities of install all of the programs required to make Spleeter work. I don't think there's a Mac version but can't say that with certainty. Manually downloading the separate files and manually commanding Spleeter will work on Mac's. There's just no all in one containing all of the necessary files at this time.

. There have been several updates to the program since this discussion and Spleeter is much improved, the download version accepts uncompressed audio files and has a bandwidth of 16k that provides much higher quality material.

. Intel Pentium & Celeron CPU's cannot run Spleeter

. I believe it still needs a manual install of vc_redist.x64 from Microsoft also. It did on my system.

.Not recommended CPU's
Intel Celeron CPU
Windows 32bit
Windows 7
Windows XP
Computers purchased prior to ~2011

Some notes regarding Spleeter and BIAB:

. The higher bandwidth capability as well as the ability to use uncompressed audio files has improved the quality of Spleeter since earlier versions and is also higher quality than what was available for free on line when I last used Spleeter on line. The site I used was restricted to 11k bandwidth and MP3 files. Also, it was common to have to have my song upload in que for hours before getting my results.

. Most of the comparisons, reviews and demonstrations I've found on YouTube have used commercial pop/rock song releases. It's not uncommon for these genre songs to have more than a hundred tracks, special effects and other production techniques applied in heavy doses. Many of the artifacts remaining in Spleeter files are a result of these heavy production and high track count.

. Spleeter works acceptably with BIAB songs. I think the lower track count and less production benefits the Spleeter program very good.

. Editing and merging Spleeter files works really good with BIAB. I do editing exclusively with the BIAB Audio Editor. Editing and changes occur in real time and I get immediate feedback and instant auditions of edits, changes and renders. Cutting/pasting, crossfades, fade ins and fade outs, gain staging, balancing audio levels and syncing tracks with BIAB tracks is seamless, quick and completely intuitive and all of these tasks can be done from the Audio Editor Window. BIAB has multiple undo levels so anytime that anything doesn't work, it can be undone instantaneously.

. BIAB offers adding harmonies and fixing 'sour notes' without having to leave the Audio Editor Window and provides instant feedback and undo if necessary.

. From the Audio Editor Window, RealTracks can be selected and generated on the Audio Channel and the 16 Utility Tracks and merged with existing audio residing on the track.

. Tracks can be converted from stereo to mono and mono to stereo in the Audio Editor Window.

. The Audio Chord Wizard and analyze and populate audio files including Spleeter files in the Audio Editor Window.

. The Audio Editor has the tools along with the BIAB suite of fx's to clean up isolated Spleeter Tracks. It easily silences artifacts and can apply EQ to correct anomalies and artifacts without the need to export to a DAW.

BIAB 2025:RB 2025, Latest builds: Dell Optiplex 7040 Desktop; Windows-10-64 bit, Intel Core i7-6700 3.4GHz CPU and 16 GB Ram Memory.