The editing features in the notation window and the PianoRoll are always "available" which can cause some confusion. As AudioTrack mentioned, if you edit notes here and the name of your track is green in the mixer, then it will not follow any edits that were made. You would notice if you erase all notes in the PianoRoll for a RealTrack that it will still play afterwards.

There are a few ways to transpose in Band-in-a-Box. Which area of the program are you going to?

If you want to transpose your whole song, click the key signature at the top of the screen and select your new key. If you wish to change your key in the middle of a song, right click a bar and go to Bar Settings. In this dialog you can change the key at the specific bar. More options for transposition are found under Edit | Transpose.

Here is also a tutorial video on "transposing from to": https://youtu.be/AbRuFD2xxN8

Best,
Chantelle