Gegu,
what version of Reaper? I don't have to go through much effort to load PG Music BIAB onto a track.
It won't have any impact but you should synch the tempos.
Have you checked the folder generated files are saved to? It may be going beyond it's nominated size...probably won't help either but worth checking.
That was a lot of regenerating...I don't do any changes or regenerations within Reaper as I feel much more comfortable doing the grunt work in the main BIAb prog...but I understand it was to get you to the crash point.
Don't worry about negativity - it's the change to Lake Michigan water that has seen the rise & rise of the curmudgeon estate.

Cheers
rayc
"What's so funny about peace, love & understanding?" - N.Lowe