That's a tritone worth of pitch change. I don't know any wind instrument that can retain the same timbre after that much change. This is one of the reasons why I have trumpets pitched in Bb, C, D, Eb, F, G and A. Also why there are soprano, alto, tenor, baritone and bass saxes, each tuned a fourth or fifth from the next one.
For voice, I don't claim to know.
What moderation approval?
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