I don’t think this is a problem. I recognize some of your devices as being around for awhile, when USB 2 was the standard. The low data transfer rates shouldn’t stress your computer unless you stumble on an IRQ conflict. That is unlikely in the days of Windows 10 and 11. The worst I can see happening is that one device doesn’t work until you try another USB port.

BIAB needs lots of storage space but not necessarily fast storage to work. The CPU is most important. You asked specifically about RAM. Even that used to be more of an issue but not now, since. BIAB 2024 and later reads the RealTracks more efficiently from disk than in past years.

BIAB 2025 Win Audiophile. Software: Studio One 7 Pro, Swam horns, Acoustica-7, Notion 6, Song Master Pro, Win 11 Home. Hardware: Intel i9, 32 Gb; Roland Integra-7, Presonus 192 & Faderport 8, Royer 121, Adam Sub8 & Neumann 120 monitors.