Studio One does have a "Release Audio Device In Background" checkbox. You might want to have a play around with that setting. Also do the sample rates of both programs match?
Also no matter which interface you're using, temporarily change to "Windows Audio", open the "Control Panel" and UN-check the "Exclusive Mode" check box.
Change your settings back to your interface and in most cases it will allow other apps to use the interface while S1 is open and/or playing audio.

I don't know if this will fix your issue but might be worth a try.


BIAB 2025 Ultrapack- Studio One Pro 7 Windows 11, Mac Mini M4 with Logic Pro 11, Melodyne Studio