My MOTU Audio Express is actually self sensing so it will auto-adapt to the same sampling rate which is being sent to it. But the sending and recieving sampling rate must be the same. You can't mix sampling rates or you will hear the crackal and popping. I think we may all be in agreement with this. I will only add, I tried to fix everythink at 48K for a long period of time, then there came a point where I just gave up and now my default everywhere is 44.1.


BIAB – 2026, Reaper (current), i7-12700F Processor, 32GB DDR4-3200MHz RAM, Motu Audio Express 6x6 - My SoundCloud.